The benefit of these tablets is that dosing is once weekly, as follows: 10 days before you enter the affected area, the second dose taken 3 days before and then continue to take on the same day of each week whilst there. They are continued for 4 weeks after leaving.
Tablets taken once per day. Treatment starts at short notice (2 days before trip) and stops 1 week after the trip (compared to 4 weeks for other anti-malarials). Malarone is notable for having far fewer side effects than other, older malaria drugs.